BioT is a lipid-based transfection reagent designed and formulated with proprietary technology for introducing DNA, siRNA and anti-sense oligonucleotides into a variety of eukaryotic cell lines and primary cells. It provides laboratories an excellent transfection reagent with high transfection efficiency, low cytotoxicity and low cost.
Features
- High transfection efficiency for a broad range of adherent cells
- Low toxicity
- Convenient to use: simple to use and very stable
Storage: 4oC recommended; Room temperature stable
Shipping: Ambient temperature
Selected publications of BioT
- Control of iron homeostasis by an iron-regulated ubiquitin ligase. Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA. Science. 2009 Oct 30; 326 (5953): 718-21.
- Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Bloom JD, Gong LI, Baltimore
D. Science. 2010 Jun 4;328(5983):1272-5.
- Antibody-based protection against HIV infection by vectored immunoprophylaxis.Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. Nature. 2011 Nov 30;481(7379):81-4.
- Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells.Nagamori I, Cruickshank VA, Sassone-Corsi P. J Cell Sci. 2011 Dec 15;124(Pt 24):4346-55.
- Regulation of Adipose Differentiation by Fructose and GluT5. Du L, Heaney AP. Mol Endocrinol. 2012 Jul 24.
- MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Stehling O, Vashisht AA, Mascarenhas J, Jonsson ZO, Sharma T, Netz DJ, Pierik AJ, Wohlschlegel JA, Lill R. Science. 2012 Jul 13;337 (6091):195-9.