BioT selected publications


  1. Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability. Caccamo A, Majumder S, Deng JJ, Bai Y, Thornton FB, Oddo S. J Biol Chem. 2009 Oct 2; 284(40):27416-24.

  2. Control of iron homeostasis by an iron-regulated ubiquitin ligase. Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA. Science. 2009 Oct 30; 326 (5953): 718-21.

  3. Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. Sahar S, Zocchi L, Kinoshita C, Borrelli E, Sassone-Corsi P. PLoS One. 2010 Jan 1;5(1):e8561.

  4. Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. Zhang Y, Liu R, Ni M, Gill P, Lee AS. J Biol Chem. 2010 Mar 5.

  5. A Quantitative and Kinetic Fusion Protein-Triggering Assay can Discern Distinct Steps in the Nipah Virus Membrane Fusion Cascade. Aguilar HC, Aspericueta V, Robinson L, Aanensen K, Lee B. J Virol. 2010 Jun 2.

  6. Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Bloom JD, Gong LI, Baltimore D. Science. 2010 Jun 4;328(5983):1272-5.

  7. Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding. Wang YE, Park A, Lake M, Pentecost M, Torres B, Yun TE, Wolf MC, Holbrook MR, Freiberg AN, Lee B. PLoS Pathog. 2010 Nov 11;6(11):e1001186.

  8. A novel mechanism of anti-apoptotic function of 78 kDa glucose-regulated protein (GRP78), an endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK). Zhou H, Zhang Y, Fu Y, Chan L, Lee AS. J Biol Chem. 2011 May 26. [Epub ahead of print]

  9. Functional phosphosite screening for targeted protein-protein interactions by combining phosphoproteomics strategies and mammalian two-hybrid assays. Guo M, Xia Z, Ma H. Mol Biosyst. 2011 Jun;7(6):1838-41. Epub 2011 Apr 12.

  10. Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance. Vergnes L, Chin R, Young SG, Reue K. J Biol Chem. 2011 Jan 7;286(1):380-90. Epub 2010 Nov 1.

  11. The Cellular Protein La Functions in Enhancement of Virus Release through Lipid Rafts Facilitated by Murine Leukemia Virus Glycosylated Gag.  Nitta T, Tam R, Kim JW, Fan H. MBio. 2011 Feb 22;2(1). pii: e00341-10. doi: 10.1128/mBio.00341-10. Print  2011.

  12. Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling. Lisse TS, Liu T, Irmler M, Beckers J, Chen H, Adams JS, Hewison M. FASEB J. 2011 Mar;25(3):937-47. Epub 2010 Dec 1.

  13. The UBC9 E2 SUMO Conjugating Enzyme Binds the PR-Set7 Histone Methyltransferase to Facilitate Target Gene Repression. Spektor TM, Congdon LM, Veerappan CS, Rice JC. PLoS One. 2011;6(7):e22785. Epub 2011 Jul 29.

  14. Ketamine Influences CLOCK:BMAL1 Function Leading to Altered Circadian Gene Expression. Bellet MM, Vawter MP, Bunney BG, Bunney WE, Sassone-Corsi P. PLoS One. 2011;6(8):e23982. Epub 2011 Aug 24.

  15. A distinct mechanism for coactivator versus corepressor function by histone methyltransferase G9a in transcriptional regulation. Purcell DJ, Jeong KW, Bittencourt D, Gerke DS, Stallcup MR. J Biol Chem. 2011 Oct 8. [Epub ahead of print]

  16. An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirus. Lee S, Salwinski L, Zhang C, Chu D, Sampankanpanich C, Reyes NA, Vangeloff A, Xing F, Li X, Wu TT, Sahasrabudhe S, Deng H, Lacount DJ, Sun R. PLoS Pathog. 2011 Oct;7(10):e1002297. Epub 2011 Oct 20.

  17. Antibody-based protection against HIV infection by vectored immunoprophylaxis.Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. Nature. 2011 Nov 30;481(7379):81-4.

  18. Lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family, is a Wnt-beta-catenin pathway target gene in human endothelial cells which regulates matrix metalloproteinase-2 expression and promotes endothelial cell invasion.Planutiene M, Planutis K, Holcombe RF. Vasc Cell. 2011 Dec 14;3:28.

  19. Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells.Nagamori I, Cruickshank VA, Sassone-Corsi P. J Cell Sci. 2011 Dec 15;124(Pt 24):4346-55. Epub 2012 Jan 5.

  20. Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS. Blood. 2012 Jan 19;119(3):817-25.

  21. HEAT Repeat 1 Motif Is Required for B56γ-containing Protein Phosphatase 2A (B56γ-PP2A) Holoenzyme Assembly and Tumor-suppressive Function. Nobumori Y, Shouse GP, Fan L, Liu X.  J Biol Chem. 2012 Mar 30;287(14):11030-6.

  22. Overexpression of SKI oncoprotein leads to p53 degradation through regulation of MDM2 protein sumoylation.Ding B, Sun Y, Huang J. J Biol Chem. 2012 Apr 27;287(18):14621-30.

  23. Regulation of Adipose Differentiation by Fructose and GluT5. Du L, Heaney AP. Mol Endocrinol. 2012 Jul 24. [Epub ahead of print]

  24. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Stehling O, Vashisht AA, Mascarenhas J, Jonsson ZO, Sharma T, Netz DJ, Pierik AJ, Wohlschlegel JA, Lill R. Science. 2012 Jul 13;337(6091):195-9.

  25. Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms. Nitta T, Lee S, Ha D, Arias M, Kozak CA, Fan H. Retrovirology. 2012 Jul 24;9:58.

  26. A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs. Hoverter NP, Ting JH, Sundaresh S, Baldi P, Waterman ML. Mol Cell Biol. 2012 Sep;32(18):3648-62.

  27. The RelB subunit of NFκB acts as a negative regulator of circadian gene expression. Bellet MM, Zocchi L, Sassone-Corsi P. Cell Cycle. 2012 Sep 1;11(17):3304-11.

  28. Characterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes. Kwong EK, Kim KM, Penalosa PJ, Chan JY. PLoS One. 2012;7(10) Epub 2012 Oct 29.

  29. Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros. Uckun FM, Ma H, Zhang J, Ozer Z, Dovat S, Mao C, Ishkhanian R, Goodman P, Qazi S. Proc Natl Acad Sci USA. 2012 Oct 30;109(44):18072-7.  

  30. Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells. Dellinger RW, Matundan HH, Ahmed AS, Duong PH, Meyskens FL Jr. PLoS One. 2012;7(10). Epub 2012 Oct 22.

  31. Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment. Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM. Cell Rep. 2012 Nov 29;2(5):1316-28.

  32.  Use of Mutated Self-Cleaving 2A Peptides as a Molecular Rheostat to Direct Simultaneous Formation of Membrane and Secreted Anti-HIV Immunoglobulins. Yu KK, Aguilar K, Tsai J, Galimidi R, Gnanapragasam P, Yang L, Baltimore D. PLoS One. 2012;7(11):e50438. Epub 2012 Nov 28.

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